Dr Adami & colleagues reply

Reply to Venturelli and colleagues.

TO THE EDITOR: The author team of our recently published manuscript (1) on improved single muscle fiber quality in the oldest-old thank Dr. Venturelli and colleagues (5) for their thoughtful appraisal of our work. Furthermore, this group is to be commended for their efforts examining force-generating capacity in the oldest-old, both in vitro and in vivo, as a means of providing additional insig...

Authors' reply to Huffman and colleagues.

1Department of Health Care Policy, Harvard Medical School, Ipswich, MA 01938, USA; 2Department of Social Science, York University, Toronto, Ontario, Canada; 3Division of Biostatistics, School of Public Health Department of Statistics, University of California, Berkeley, CA, USA; 4Therapeutics Initiative, Departments of Anesthesiology, Pharmacology and Therapeutics and Medicine, University of Br...

Dr. Wallace and Dr. Stone reply.

Reply to Dr. Weiskirchen.

TO THE EDITOR: We would like to thank Dr. Weiskirchen (5) for his interest in our recent publication (3). As we mentioned in the DISCUSSION and as pointed out by Dr. Weiskirchen, the absence of protein data in our adenovirus model represents a limitation of our study. Regarding the RNA expression, we also expected to find a greater difference in ccn1/cyr61 gene expression in the mice instilled ...

Authors' reply to Lin and colleagues.

1Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland; 2Department of Surgical Sciences, Section of Orthopaedics, Uppsala University, Uppsala, Sweden; 3Department of Hand Surgery, Tampere University Hospital, Tampere, Finland; 4Centre for Statistics in Medicine, Botnar Research Centre, University of Oxford, Oxford, UK; 5...